卟啉金属化对氢键组装的卟啉-蒽醌衍生物超分子稳定性影响

分别研究了 5_(对_羧基亚甲基 )苯基_10 ,15 ,2 0_三 (对_甲基 )苯基卟啉 (p_CMPTTP)及其锌 (Ⅱ )配合物Zn(p_CMPTTP)与 (1_氨基 )蒽醌 (AAQ)通过氢键的超分子自组装。根据静态猝灭过程的描述式由荧光光谱滴定数据计算了它们的结合常数 ,发现锌 (Ⅱ )配合物与AAQ超分子的结合常数小于自由羧卟啉与AAQ超分子的结合常数。这可能是由于卟啉的金属化作用对超分子不对称氢键强度的影响引起的。     

制造模式变迁的动力机制及其特征分析

制造模式变迁过程受制于三类因素，即制造模式现有状态、制造模式的四大基本维度（技术与方法、文化、组织结构以及和谐管理)和外部环境中的随机涨落因素。该过程表现出非平衡相变、对称性破缺、分叉等特征。当新的制造模式形成时，其研发投入、文化、组织结构及其管理、知识调配都须有很大的变动和调整。     

天然产物研究与自然资源的可持续性开发利用

结合学科特点，就天然产物研究及自然资源的可持续性开发利用作了几点讨论。     

A Study of Evaluation System of Restricting Factors in Training Students‘ Qualities

This paper studies evaluation system of restricting factors in training students' qualities by modern mathematical method of analysis hierarchy process and principal factor analysis, and to build up a mathematical model of evaluation system.     

信息技术与学科教学的整合需要研究型教师

信息技术与学科的有效整合需要教师具备整合的基本能力，并成为研究型教师。指出教师要不断更新信息技术知识和技能，利用现代教学设施，依据教学实践开展研究，从而探索出有效的整合模式。     

Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat

Summary The administration of 15(R)-15-methyl prostaglandin E₂ (15(R)-15-M-PGE₂) in vivo significantly diminished the uptake of⁵⁹Fe into blood, spleen, liver, femur and dried intestine of rats, whereas acetylsalicylic acid (ASA) increased the counts significantly. This effect of ASA was counteracted by 15(R)-15-M-PGE₂. It is suggested that prostaglandins (PGs) might play an important role in inhibiting iron absorption at the intestinal level.This work was supported by grant No.6638 from CONICET (Argentina). The technical assistance of Mrs María E. Castro and Norma Rizzo is gratefully acknowleged.     

供应链中的时滞

研究供应链中时滞对长鞭效应的影响 .建立了供应链的多级库存控制系统模型 ,给出了其系统方框图及传递函数 ,求出了使整个供应链稳定的临界条件 .指出长鞭效应产生的原因是由于在系统时滞及系统增益的共同作用下使得供应链中各子系统产生衰减振荡或发散振荡的结果 .最后提出了减弱长鞭效应的四种方法.     

Energetic landscape of alpha-lytic protease optimizes longevity through kinetic stability.

During the evolution of proteins the pressure to optimize biological activity is moderated by a need for efficient folding. For most proteins, this is accomplished through spontaneous folding to a thermodynamically stable and active native state. However, in the extracellular bacterial alpha-lytic protease (alphaLP) these two processes have become decoupled. The native state of alphaLP is thermodynamically unstable, and when denatured, requires millennia (t1/2 approximately 1,800 years) to refold. Folding is made possible by an attached folding catalyst, the pro-region, which is degraded on completion of folding, leaving alphaLP trapped in its native state by a large kinetic unfolding barrier (t1/2 approximately 1.2 years). alphaLP faces two very different folding landscapes: one in the presence of the pro-region controlling folding, and one in its absence restricting unfolding. Here we demonstrate that this separation of folding and unfolding pathways has removed constraints placed on the folding of thermodynamically stable proteins, and allowed the evolution of a native state having markedly reduced dynamic fluctuations. This, in turn, has led to a significant extension of the functional lifetime of alphaLP by the optimal suppression of proteolytic sensitivity.     

一种混沌神经网络模型及其在优化中的应用

通过在Hopfield神经网络模型 (HNN)中引入非线性自反馈项 ,提出了一种具有暂态混沌动力学行为的神经网络模型。该模型首先经过一个倍周期倒分叉过程进行混沌搜索 ,进而进行类似HNN的梯度搜索。由于它利用了混沌搜索固有的随机性和轨道遍历性 ,因而具有较强的克服陷入局部极小的能力。两个典型的函数优化例子表明了该算法的有效性     

Comparative study of the karyotypes of two Egyptian species of bats,Taphozous perforatus andTaphozous nudiventris (Chiroptera: Mammalia)

A detailed karyotypic analysis of two Egyptian species of bats,Taphozous perforatus andTaphozous nudiventris, was made on the basis of conventional data and G-band patterns. No detectable karyotypic difference was found between the two species (2n=42, F.N. 64). By comparison of G-band patterns, some differences between the two species were seen in the corresponding autosomal pairs. These results are reported for the first time in Egypt.